comparison of electrophysiological findings in axonal and demyelinating guillain-barre syndrome.
نویسندگان
چکیده
background: incidence and predominant subtype of guillain-barre syndrome (gbs) differs geographically. electrophysiology has an important role in early diagnosis and prediction of prognosis. this study is conducted to determine the frequent subtype of gbs in a large group of patients in iran and compare nerve conduction studies in axonal and demyelinating forms of gbs. methods: we retrospectively evaluated the medical records and electrodiagnostic study (eds) of 121 gbs patients who were managed in our hospital during 11 years. after regarding the exclusion criteria, patients classified as three groups: acute inflammatory demyelinating polyneuropathy (aidp), acute motor axonal neuropathy (aman), and acute motor sensory axonal neuropathy (amsan). the most frequent subtype and then electrophysiological characteristic based on the time of eds and their cerebrospinal fluid (csf) profile were assessed. results: among 70 patients :nally included in the study, 67% w re men. about 63%, 23%, and 14% had aidp, aman, and amsan, respectively.aidp patients represented a wider range of ages compared with other groups. higher levels of csf protein, abnormal late responses and sural sparing were more frequent in aidp subtype. five amsan patients also revealed sural sparing. conduction block (cb) was observed in one aman patient. prolonged f-wave latency was observed only in aidp cases. cb and inexcitable sensory nerves were more frequent after 2 weeks, but reduced f-wave persistency was more prominent in the early phase. conclusion: aidp was the most frequent subtype. although the electrophysiology and csf are important diagnostic tools, classification should not be made based on a distinct finding.
منابع مشابه
Comparison of electrophysiological findings in axonal and demyelinating Guillain-Barre syndrome
BACKGROUND Incidence and predominant subtype of Guillain-Barre syndrome (GBS) differs geographically. Electrophysiology has an important role in early diagnosis and prediction of prognosis. This study is conducted to determine the frequent subtype of GBS in a large group of patients in Iran and compare nerve conduction studies in axonal and demyelinating forms of GBS. METHODS We retrospective...
متن کاملEPIDEMIOLOGICAL, CLINICAL AND ELECTRODIAGNOSTIC FINDINGS IN CHILDHOOD GUILLAIN-BARRE SYNDROME
In order to identify the clinical and electrophysiological characteristics of childhood Guillain-Barre Syndrome (GBS) in East Azarbaijan province, clinical and electrophysiological data on 40 consecutive children with GBS, admitted to Tabriz Children's Medical Center from March 21st 1999 to March 20th 2002, were analyzed. All patients received intravenous immunoglobulin, 400 mg /kg/ day fo...
متن کاملElectrophysiological Changes in Acute Guillain-barre Syndrome
Aim: To study the various electrophysiological changes in the motor conduction, sensory conduction and F wave latencies of acute Guillain-Barre Syndrome patients. Methods: Sixteen patients with acute GBS were included in this study. They were subjected to various nerve conduction studies (NCS) following standardized procedures. The mean values obtained for the various nerve conduction parameter...
متن کاملPrediction of Functional Outcome in Axonal Guillain-Barre Syndrome
OBJECTIVE To identify the factors that could predict the functional outcome in patients with the axonal type of Guillain-Barre syndrome (GBS). METHODS Two hundred and two GBS patients admitted to our university hospital between 2003 and 2014 were reviewed retrospectively. We defined a good outcome as being "able to walk independently at 1 month after onset" and a poor outcome as being "unable...
متن کاملTen-year Investigation of Clinical and Laboratory Findings in children with Guillain-Barre Syndrome in Sari Bou-Ali Sina Hospital
Background and purpose: Guillain-Barre syndrome (GBS) is an autoimmune disorder that has different clinical and pathologic findings. Its diagnosis is based on clinical findings. This study aimed at investigating the characteristics of the disease in a region in north of Iran. Materials and methods: In this descriptive-analytical study, the records (2008-2018) of children under the age of 15 ye...
متن کاملمنابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
عنوان ژورنال:
iranian journal of neurologyجلد ۱۳، شماره ۳، صفحات ۱۳۸-۱۴۳
میزبانی شده توسط پلتفرم ابری doprax.com
copyright © 2015-2023